Why zebrafish ?

Zebrafish is an unique model in neuroscience; key neurological pathways are well conserved and we can used genetics and pharmacological tools to investigate brain functions. This model is also suitable for large-scale approaches and drug discovery efforts

Neurobiology of opioid addiction

We are using a unique opioid self-administration assay to study the molecular pathways involved in drug seeking behaviour. 

Impact of neurosteroids on behaviour

Using large scale approaches we are interested in studying the neurological impact of unique neurosteroids. 

Long-term consequences of neonatal opioid exposure

We are generating a new zebrafish model to study the behavioural and molecular impact of embryonic opioid exposure

We are using a range of techniques from behavioural platforms, imaging, genetic tools (transgenic lines, CRISPR-Cas9) and pharmacological tools

Neuronal activity in live zebrafish larvae 

Small molecule screening and drug discovery

Novel object assay to monitor learning and memory