Why zebrafish ?
Zebrafish is an unique model in neuroscience; key neurological pathways are well conserved and we can used genetics and pharmacological tools to investigate brain functions. This model is also suitable for large-scale approaches and drug discovery efforts
Neurobiology of opioid addiction
We are using a unique opioid self-administration assay to study the molecular pathways involved in drug seeking behaviour.
Impact of neurosteroids on behaviour
Using large scale approaches we are interested in studying the neurological impact of unique neurosteroids.
Long-term consequences of neonatal opioid exposure
We are generating a new zebrafish model to study the behavioural and molecular impact of embryonic opioid exposure
We are using a range of techniques from behavioural platforms, imaging, genetic tools (transgenic lines, CRISPR-Cas9) and pharmacological tools
Neuronal activity in live zebrafish larvae
Small molecule screening and drug discovery
Novel object assay to monitor learning and memory